Probiotic strain Lactobacillus plantarum v increases iron absorption from an iron-supplemented fruit drink: a double-isotope cross-over. Il sovraccarico marziale si può verificare o a causa di un'alterazione congenita dei meccanismi che regolano l'assorbimento intestinale del ferro, quale si verifica. Con il nome di sideroforo si indica una piccola molecola con elevata affinità per il ferro e in Negli eucarioti, altre strategie per migliorare la solubilità del ferro e l'assorbimento sono l'acidificazione dell'ambiente circostante (ad esempio.


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Probiotic strain Lactobacillus plantarum v increases iron absorption from an iron-supplemented fruit drink: Abstract Iron assorbimento del ferro is common, especially among young women. Adding probiotics to foods could be one way to increase iron absorption.

The aim of this study was to test the hypothesis assorbimento del ferro non-haem iron absorption from a fruit drink is improved by adding Lactobacillus plantarum v Lpv.


Iron absorption was studied in healthy women of reproductive age using a single-blind cross-over design in two trials applying the double-isotope 55Fe and 59Fe technique. In Trial 1, iron absorption from a fruit drink containing colony-forming units CFU Assorbimento del ferro was compared with that from a control drink without Lpv.

Trial 2 had the same design but CFU were used. The test and control drinks contained approximately 5 mg of iron as ferrous lactate and were labelled with 59Fe B and 55Fe Arespectively, and consumed on 4 consecutive days assorbimento del ferro the order AABB.

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assorbimento del ferro Retention of the isotopes was measured with whole-body counting and in blood. Probiotics, Lactobacillus plantarum v, Fruit drinks, Iron status, Radio iron, Radioisotopes, Females Iron deficiency and low iron status are common all around the globe 1and women of reproductive age are a vulnerable population because of their high iron requirements 23.

Besides inadequate iron intake, low iron bioavailability is the predominant reason for iron deficiencies in populations subsisting on plant-based diets, independent of sex 4.

Strategies to increase the intake of foods rich in iron, as assorbimento del ferro as dietary factors with enhancing effect on iron absorption, are therefore important. A number of dietary factors a ffect the absorption of non-haem iron.

Meccanismo di assorbimento del ferro

Intake of ascorbic acid and meat stimulates absorption, whereas calcium, polyphenols e. Lactic acid-fermented foods may also improve the non-haem iron absorption. A number of single-meal studies with fermented vegetables and cereals have shown a significant increase in iron absorption in humans 6 — 8.

Lactic acid-fermented foods can increase iron absorption in humans, possibly by lowering pH, activating phytases, producing organic acids or by the viable lactic acid bacteria.

The strain Lactobacillus plantarum v Lpv has been shown to survive the passage through the gastrointestinal tract irrespective of gastric acidity 9. The strain colonises the intestine and can be found in mucosal samples taken from the jejunum and rectum 11 d after administration In clinical studies, Lpv has been shown to have a positive effect on health.

Effects include reducing gas problems and pain assorbimento del ferro — assorbimento del ferro in people who suffer from irritable bowel syndrome.


Intake of Lpv can also counteract certain unwanted bacteria in the intestine 14and it can also have an anti-inflammatory effect by reducing the content of fibrinogen, ROS and IL-6 assorbimento del ferro the serum of subjects in a proinflammatory state 15 The primary aim of the study was to test the hypothesis that non-haem iron absorption from a fruit drink is improved by the addition of Lpv.

The secondary aim was to investigate whether this hypothesised effect is dependent on the Lpv concentration by giving the subjects a dose of or CFU Lpv. Methods Design The study comprised two cross-over double radio-iron isotope single-blinded trials in young healthy Swedish women.

The reason for confining the study to women was that women are one assorbimento del ferro the main vulnerable populations when it comes to iron deficiency. This double radio-iron method enabled the effect of adding or not adding Lpv on iron absorption to be measured separately in the same individual.

The two separate trials were performed from August to December General protocol In each trial, eleven subjects were served either a ml fruit drink containing Lpv B or assorbimento del ferro ml fruit drink without lactobacilli A.

The fruit drink was served as breakfast during 4 consecutive days in the order AABB.